Choose Font Size: A
| |

Azithromycin

Generic Name (active ingredient): Azithromycin
Brand Name: Zithromax, Sumamed

Azithromycin is a broad spectrum bacteriostatic antibiotic. Azithromycin is a drug of choice in the treatment of sexually transmitted infections such as ( chlamydia infection, gonorrhea, bacterial prostatitis, gonorrheal cervicitis, gonorrheal urethritis, ureoplasmosis and mycoplasmosis. It is effective agains Helicobacter pylori infections.

How does the medication work?
Azithromycin is a broad spectrum macrolide antibiotic, azalide derivative. Azithromycin exerts bacteriostatic action that is related to suppressing the synthesis of proteins in microbial cell. Azithromycin binds to 50S ribosome subunits, inhibits peptidyl translocase at the stage of translation and thus suppresses protein synthesis. Azithromycin slows down growth and replication of bacteria. Azithromycin is active against gram positive cocci, gram-negative microorganisms, certain anaerobic microorganisms.

When Azithromycin is prescribed?
Azithromycin is used to treat infections caused by sensitive to the medication microorganisms:

  • ENT and upper respiratory tract infections (tonsillitis, sinusitis, pharyngitis, otitis media)
  • Infections of the lower respiratory system
  • Scarlet fever
  • Skin and soft tissue infections (erysipelas, impetigo, secondary infected dermatosis
  • Infections of the urogenital system (gonorrheal urethritis, cervicitis)
  • Lyme disease-for the treatment of initial stage ((erythema migrans)
  • Stomach and duodenal ulcers associated with Helicobacter pylori
  • Sexually transmitted diseases such as gonorrhea, chlamydia, chancroid

Azithromycin is not intended for treatment of viral and fungal infections

What should I know before taking Azithromycin?
Do not use this medication if you are allergic to Azithromycin or to any other medicines such as:

  • Erythromycin, Roxithromycin and other macrolide antibiotics

Do not take Azithromycin if any of the below conditions apply to you:

  • Severe liver diseases including hepatic failure, cirrhosis,
  • Severe kidney diseases including renal failure, pyelonephritis, glomerulonephritis
  • Children age
  • Severe Cardiovascular diseases
  • Myasthenia gravis
  • Breastfeeding
  • Pregnancy

If you are pregnant, plan to become pregnant, or breastfeed, you should take Azithromycin only under a strict control of your doctor. Azithromycin belongs to a pregnancy category B meaning that the safety of medication in pregnant women has not been studied. You should talk to your doctor about all risks and benefits of taking Azithromycin during pregnancy.

Before taking Azithromycin, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • If you are upcoming any surgical interventions
  • Arrhythmia
  • Liver or kidney diseases in anamnesis

How to take Azithromycin:
Azithromycin is available in the forms of capsules, coated tablets, oral suspension, solution for infusion.
Capsules, coated tablets and suspension are taken orally (by mouth). Solution for infusion is administered only intravenously by drop infusion. Solution for infusion must not be administered intramuscularly or intravenously by stream infusion.

Dosage of Azithromycin is prescribed individually by physician.

Take the entire amount of Azithromycin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Azithromycin?
Azithromcyin is usually well tolerated and side effects are uncommon. The most common side effects associated with Azithromycin include:

  • Nausea
  • Diarrhea
  • Vomiting
  • Stomach pain
  • Headache
  • Skin rash

Other Azithromycin side effects include: itching, hives, swelling, shortness of breath, bloody stool. In very rare cases the medication may cause: constipation, heartburn, hypotension, tinnitus, oral yeast infections, vaginal yeast infections, dehydration, paresthesia, kidney failure

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Azithromycin overdose symptoms?
If you overdose Azithromycin, seek immediate medical attention. Overdose symptoms include: nausea, temporar loss of hearing, diarrhea, stomach pain, liver dysfunction

Which other medicines may affect Azithromycin?
Azithromycin may interact with the following groups of drugs:

  • Blood thinners
  • Antacids
  • Cardiac glycosides (digoxin)
  • Immunosuppressors
  • Anticonvulsants (antiepileptics)
  • Insomnia treatment
  • Ergot alkoloids
  • Xantines
  • Antivirals

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Azithromycin, let your doctor know what other medicines, including OTC, you currently take.

How should I store Azithromycin?
You should store the medication at dry and protected from light place out of reach of children. Do not store the medication in the bathroom.