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Generic Name (active ingredient): Fluconazole
Brand Name: Fluconazole
Fluconazole is a synthetic antifungal medication from the triazoles group, mainly intended for treatment of candidiasis and other mycoses.
How does the medication work?
Fluconazole possesses a highly specific effect, inhibiting the enzyme activity of fungi that are dependent on cytochrome P450. It suppresses the conversion of fungi cells' lanosterol into ergosterol, increases the permeability of cell membrane, violates its growth and replication. Fluconazole, being highly selective for fungal cytochrome P450, practically does not inhibit these enzymes in the body and does not have anti-androgenic activity. The medication is active in opportunistic mycoses, including those caused by Candida spp. (including generalized forms of candidiasis in the background of immunosuppression), Cryptococcus neoformans and Coccidioides immitis (including intracranial infection), Microsporum spp. and Trichophyton spp; in endemic mycosis caused by Blastomyces dermatidis, Histoplasma capsulatum (including with immunosuppression).
When Fluconazole is prescribed?
What should I know before taking Fluconazole?
Do not use this medication if you are allergic to Fluconazole or to any other medicines such as:
Do not take Fluconazole if any of the below conditions apply to you:
Before taking Fluconazole, tell your health care provider about any other medicines you take or if you have any of the following disorders:
If you are pregnant, plan to become pregnant, or breastfeed, you should take Fluconazole only under a strict control of your doctor. Fluconazole belongs to the pregnancy category C meaning that it is not known whether it will be harmful to the fetus.
How to take Fluconazole:
Fluconazole is available in the forms of capsules, powder for suspension for oral administration, solution for infusion, syrup, tablets
Dosage of Fluconazole is prescribed individually by physician.
Take the entire amount of Fluconazole prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking the medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.
What are the side effects of Fluconazole?
Fluconazole may cause the following side effects:
If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.
Which are Fluconazole overdose symptoms?
If you overdose Fluconazole, seek immediate medical attention. Overdose symptoms include: hallucinations, paranoid behavior
Which other medicines may affect Fluconazole?
Fluconazole may interact with the following groups of drugs:
For a complete list of possible interactions ask your doctor or pharmacist. Before taking Fluconazole, let your doctor know what other medicines, including OTC, you currently take.
How should I store Fluconazole?
Store Fluconazole at room temperature. Keep away from heat, moisture, and light, and out of the reach of children.