|Antimicrobial preparations||Antituberculosis drugs||Antifungal drugs||Antiviral preparations||Antiprotozoal drugs||Antihelmintic drugs||Other antibiotics|
Generic Name (active ingredient): Lamivudine
Brand Name: Zeffix, Epivir
Lamivudine is antiviral preparation that selectively inhibit replication of HIV-1 and HIV-2 viruses, it is highly effective against hepatitis B virus (HBV).
How does the medication work?
Lamivudine is antiviral preparation-nucleoside analogue. It is highly effective against hepatitis B virus. In infectious and non-infectious cells lamivudine is metabolized into its active form-lamivudine triphosphate-which serves as substrate for DNA-polymerase of viral hepatitis B. Lamivudine embeds into viral DNA and then blocks the further formation of DNA chain. Lamivudine does not act on DNA in mammals.
Lamivudine is mild inhibitor of RNA and DNA-dependent HIV reverse transcriptase. It is active against hiv strains resistant to zidovudine.
When Lamivudine is prescribed?
What should I know before taking Lamivudine?
Do not use this medication if you are allergic to Lamivudine or to any other medicines such as:
Do not take Lamivudine if any of the below conditions apply to you:
Before taking Lamivudine, tell your health care provider about any other medicines you take or if you have any of the following disorders:
If you are pregnant, plan to become pregnant, or breastfeed, you should take Lamivudine only under a strict control of your doctor. Lamivudine belongs to a pregnancy category C meaning that it may not be safe to use this drug during pregnancy.
How to take Lamivudine:
Lamivudine is available in the form of solution and tablets. These medications are taken by mouth one or two times daily. You should strictly follow all doctor's recommendation during the treatment with Lamivudine. Missing doses can increase the chance of the virus developing resistance to lamivudine. Dosage of Lamivudine is prescribed individually by physician.
Take the entire amount of Lamivudine prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.
What are the side effects of Lamivudine?
Lamivudine may cause the following side effects:
If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.
Which are Lamivudine overdose symptoms?
If you overdose Lamivudine, seek immediate medical attention. The symptoms of overdose are not know. Most probably Lamivudine in high doses may cause effects similar to side effects.
Which other medicines may affect Lamivudine?
Lamivudine may interact with the following groups of drugs:
For a complete list of possible interactions ask your doctor or pharmacist. Before taking Lamivudine, let your doctor know what other medicines, including OTC, you currently take.
How should I store Lamivudine?
Lamivudine tablets and solution should be stored and dry and protected from light place out of reach of children. Do not store the medication in the bathroom.