Lincomycin

Generic Name (active ingredient): Lincomycin

Lincomycin is lincosamide antibiotic that us used to treat bacterial infections caused by susceptible to lincomycin microorganisms.

How does the medication work?
Lincomycin belongs to a group of antibiotics called lincosamides. In therapeutic doses the medication possesses bacteriostatic action. In high doses lincomycin may exert bactericidal action. Action mechanism is associated with inhibiting protein synthesis of microbial cells. Lincomycin is active against gram-positive microorganisms: aerobic cocci-Staphylococcus spp, Streptococcus pneumoniae, Corynebacterium diphtheriae and anaerobic spore-forming bacteria Clostridium spp. The medication is active against gram-negative anaerobic microorganism: Bacteroides spp., Mycoplasma spp.
The majority of gram-negative bacteria, fungi, viruses, protozoa.

When Lincomycin is prescribed?

  • Sepsis
  • Osteomyelitis and other infectious bone and joint damages
  • Septic endocarditis
  • Pneumonia
  • Lung abscess
  • Pleural empyema
  • Wound infections
  • Meningitis

Lincomycin can be used as a preparation of reserve in the treatment of infections caused by staphylococci strains and other gram-positive microorganisms resistant to penicillins and other antibiotics.

What should I know before taking Lincomycin?
Do not use this medication if you are allergic to Lincomycin or to any other medicines such as:

  • Clindamycin and other lincosamides

Do not take Lincomycin if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients
  • Severe liver and kidney diseases
  • Pregnancy
  • Breastfeeding

Before taking Lincomycin, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Liver diseases in anamnesis
  • Kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Lincomycin only under a strict control of your doctor. Lincomycin belongs to a pregnancy category C meaning that it is not safe to use the medication during pregnancy. Lincomycin can be harmful to an unborn baby due to its teratogenic effect.

How to take Lincomycin:
Lincomycin is available in the form of tablets and capsules. Dosage of Lincomycin is prescribed individually by physician.

Take the entire amount of Lincomycin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Lincomycin?
Lincomycin may cause the following side effects:

  • Digestive system: nausea, vomiting, epigastric pain, diarrhea, glossitis, stomatitis, transient increase in liver transaminases and bilirubin in the blood plasma, in high doses pseudomembranous colitis is possible.
  • Hemopoietic system: the reversible leukopenia, neutropenia, thrombocytopenia.
  • Allergic reactions: urticaria, exfoliative dermatitis, Quincke's edema, anaphylactic shock.
  • Other:: candidiasis.
  • Local reactions: phlebitis at the injection site
  • During rapid i/v administration: lowering blood pressure, dizziness, weakness, relaxation of skeletal muscles.

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Lincomycin overdose symptoms?
If you overdose Lincomycin, seek immediate medical attention. Overdose symptoms include: chest pain, feeling light-headed, or fainting.

Which other medicines may affect Lincomycin?
Lincomycin may interact with the following groups of drugs:

  • Bactericidal and bacteriostatic antibiotics such as penicillins, cephalosporins, macrolides, aminoglycosides
  • Muscle relaxations
  • Inhalation anaesthesia
  • Anti-diarrheal preparations

Lincomycin is not compatible with ampicillin, barbiturates, theophylline, calcium gluconate, heparin, magnesium sulphate, kanamycin, novobiocin
For a complete list of possible interactions ask your doctor or pharmacist. Before taking Lincomycin, let your doctor know what other medicines, including OTC, you currently take.

How should I store Lincomycin?
You store the medication at dry and protected from light place out of reach of children. Do not store lincomycin on the bathroom.

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