Mebendazole

Generic Name (active ingredient): Mebendazole
Brand Name: Vermox

Mebendazole is highly effective antihelminthic medication with a broad spectrum of activity against nematodes, cestodes, including: Helminthiasis, hookworm disease, strongyloidiasis, trichocephalosis, trichinosis, teniasis, echinococcosis, mixed helminthiasis.

How does the medication work?
Mebendazole is a highly effective antihelmonthin drug with a broad action spectrum. Mebendazole is highly effective against enterobiasis and trichocephalosis. It works by preventing formation of cellular tubulin in helminths that impair the function of the cytoplasmic microtubules, utilization of glucose and inhibits the production of ATP.

When Mebendazole is prescribed?

  • Enterobiasis
  • Ascariasis
  • Miner
  • Strongyloidiasis
  • Trichocephalosis
  • Trichinosis
  • Teniasis
  • Echinococcosis
  • Alveococcosis
  • Capillariasis
  • Gnathostomosis
  • Mixed helminthiasis.

What should I know before taking Mebendazole?
Do not use this medication if you are allergic to Mebendazole or to any other medicines such as:

  • Albendazole and other azole preparations

Do not take Mebendazole if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients
  • Non-specific ulcerous colitis
  • Crohn's disease
  • Hepatic failure
  • Children under 2 years of age
  • Pregnancy
  • Breastfeeding

Before taking Mebendazole, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Kidney diseases in anamnesis
  • Liver diseases in anamnesis
  • History of liver enzymes elevations

If you are pregnant, plan to become pregnant, or breastfeed, you should take Mebendazole only under a strict control of your doctor. Mebendazole belongs to a pregnancy category C meaning that the

How to take Mebendazole:
Mebendazole is available in the forms of tablets. Mebendazole tablets should be taken orally swallowing whole without chewing. Dosage of Mebendazole is prescribed individually by physician.

Take the entire amount of Mebendazole prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Mebendazole?
Mebendazole may cause the following side effects:

  • Gastrointestinal tract and liver: abdominal pain, diarrhea, nausea and vomiting, abnormal liver function, increase in liver transaminases or the development of hepatitis.
  • Central nervous system: headache.
  • Hemopoietic system: neutropenia, anemia, eosinophilia.
  • Allergic reactions: skin rash, urticaria, angioedema.
  • Other: alopecia, hematuria, cylindruria

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Mebendazole overdose symptoms?
If you overdose Mebendazole, seek immediate medical attention. Overdose symptoms include: abdominal pain, nausea, vomiting, diarrhea

Which other medicines may affect Mebendazole?
Mebendazole may interact with the following groups of drugs:

  • Insulin
  • Lipophilic medications
  • H2 histamine receptor blocker (cimetidine)
  • Anticonvulsant (carbamazepine)
  • Other microsomal liver inductors or inhibitors

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Mebendazole, let your doctor know what other medicines, including OTC, you currently take.

How should I store Mebendazole?
Mebendazole tablets should be stored at dry and protected from light place out of reach of children. Do not store the medication in the bathroom.

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