Choose Font Size: A
| |

Meropenem

Generic Name (active ingredient): Meropenem
Brand Name: Merrem, Meronem

Meropenem is an antibiotic carbapenems group. It is used in severe infections of different localization, including nosocomial, often as the reserve drug, but in life-threatening infections it can be considered as a matter of empirical therapy.

How does the medication work ?
Meropenem has a bactericidal action due to violation of the synthesis of the bacterial cell wall. It is active against most aerobic and anaerobic gram-positive and gram-negative bacteria. Xanthomonas maltophilia, Enterococcus faecium, methicillin-resistant strains of Staphylococcus spp. are resistant to Meropenem. Meropenem is resistant to the action of β-lactamases.

When Meropenem is prescribed ?
For IV administration:

  • treatment of heavy flow infectious and inflammatory diseases caused by one or more susceptible to agents: pneumonia, including hospital, urinary tract, abdominal, pelvic (including endometritis) infections, skin and soft tissues infections, meningitis, septicemia
  • For IM administration: exacerbation of chronic bacterial bronchitis, uncomplicated urinary tract infections

What should I know before taking Meropenem?
Do not use this medication if you are allergic to Meropenem or to any other medicines such as:

  • carbapenems

If you are pregnant, plan to become pregnant, or breastfeed, you should take Meropenem only under a strict control of your doctor. Meropenem belongs to a pregnancy category B meaning that during pregnancy and lactation (breastfeeding) the use of the drug is only possible in cases where the expected benefit of therapy for the mother exceeds the potential risk to the fetus or child. Experimental studies have shown that meropenem is excreted in the breast milk.

How to take Meropenem:
Meropenem is available in the form of powder for infusions.

Dosage of Meropenem is prescribed individually by physician.

Take the entire amount of Meropenem prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return. If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Meropenem ?
Meropenem may cause the following side effects:

  • digestive system: abdominal pain, nausea, vomiting, diarrhea, reversible increase in the level of bilirubin, transaminases, alkaline phosphatase and LDH
  • blood coagulation system: reversible thrombocytopenia, eosinophilia, neutropenia
  • allergic reactions: itching, rash, urticaria
  • nervous system: headache, paresthesia
  • effects due to chemotherapeutic action: oral candidiasis, vaginal candidiasis, pseudomembranous colitis
  • local reactions: inflammation, thrombophlebitis, pain at the injection site

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Meropenem overdose symptoms ?
If you overdose Meropenem, seek immediate medical attention. Overdose symptoms include: nausea, diarrhea, abdominal pain.

Which other medicines may affect Meropenem ?
Meropenem may interact with the following groups of drugs:

  • anti-gout drugs
  • β-lactams

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Meropenem, let your doctor know what other medicines, including OTC, you currently take.

How should I store Meropenem ?
Store the drug in a cool dry place out of the reach of children and pets.