Other antibiotics / Mupirocin
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Mupirocin

Generic Name (active ingredient): Mupirocin
Brand Name: Bactroban

Mupironic is a broad spectrum antibiotic for local application. In minimal doses the medication exerts possesses bacteriostatic action, in high doses - bactericidal. It is used to treat bacterial infections caused by susceptible to the medication microorganisms such as: impetigo, folliculitis, furunculosis and others.

How does the medication work?
Mupironic is a broad spectrum antibiotic for local application. It is produced by Pseudomonas fluorescens. Action mechanism of mupirocin is associated with inhibiting the enzyme Isoleucyl-tRNA synthetase that is necessary for synthesis of proteins in bacterial cells. By suppressing this enzyme, Mupirocin prevents protein synthesis. In low doses the medication exerts bacteriostatic action, in high doses - bactericidal.

When Mupirocin is prescribed?
For ointment:
Treatment of primary infections: impetigo, folliculitis, furunculosis,
Treatment of secondary infections: infectious eczema, trauma
Prophylaxis of bacterial infections of small wounds and lesions

For intranasal ointment:
Bacterial infection of the nasal cavity caused by Staphylococcus aureus

What should I know before taking Mupirocin?
Do not take Mupirocin if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients
  • Pregnancy
  • Breastfeeding

Before taking Mupirocin, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Liver diseases in anamnesis
  • Kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Mupirocin only under a strict control of your doctor. Mupirocin belongs to a pregnancy category B meaning that safety of the medication was not studied in pregnant women.

How to take Mupirocin:
Mupirocin is available in the form of ointment and intranasal ointment. The medication is used only locally. Dosage of Mupirocin is prescribed individually by physician.

Take the entire amount of Mupirocin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Mupirocin?
Mupirocin may cause the following side effects:

  • For ointment: itching, irritation, painful sensation, allergic reactions
  • For intranasal ointment: rhinitis

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Mupirocin overdose symptoms?
If you overdose Mupirocin, seek immediate medical attention. There are no known any adverse effects associated with mupironic overdose.

Which other medicines may affect Mupirocin?
Mupirocin may interact with the following groups of drugs:

  • Topical corticosteroids

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Mupirocin, let your doctor know what other medicines, including OTC, you currently take.

How should I store Mupirocin?
Mupirocin should be stored at dry and protected from light place out of reach of children.