Other antibiotics / Nitroxoline
Choose Font Size: A
| |

Nitroxoline

Generic Name (active ingredient): Nitroxoline

Nitroxoline is antimicrobial preparation with a broad spectrum of antibacterial activity. It is effective against urinary tract infections caused by susceptible to nitroxoline microorganisms: cystitis, urethritis, pyelonephritis, infectious adenoma of the prostate.

How does the medication work?
Nitroxoline is antimicrobial preparation with a broad spectrum of antibacterial activity, derivative of 8-oxyquinolines. Nitroxoline actively inhibits the synthesis of bacterial DNA. Nitroxoline is active against gram-positive and gram-negative microorganisms. The spectrum of antibacterial activity include the majority of bacteria that cause urinary tract infections.

When Nitroxoline is prescribed?
Nitroxoline is used to treat acute and chronic diseases of the urogenital system caused by sensitive to the medication microorganism:

  • Cystitis
  • Urethritis
  • Pyelonephritis
  • Epididymitis
  • Prostatitis
  • Infectious adenoma and carcinoma of the prostate gland
  • Prophylaxis of infections during surgical interventions

What should I know before taking Nitroxoline?
Do not use this medication if you are allergic to Nitroxoline or to any other medicines such as:

  • 8-oxyquinolines derivatives

Do not take Nitroxoline if any of the below conditions apply to you:

  • Severe liver dysfunction
  • Deficiency of G6PD
  • Cataract
  • Neuritis
  • Polyneuritis
  • Hypersensitivity to any of the medication ingredients
  • Pregnancy
  • Breastfeeding

Before taking Nitroxoline, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Liver diseases in anamnesis
  • Kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Nitroxoline only under a strict control of your doctor. Nitroxoline belongs to a pregnancy category B meaning that the safety of the medication was not studied in pregnant women.

How to take Nitroxoline:
Nitroxoline is available in the form of tablets. Nitroxoline tablets should be taken orally swallowing with sufficient amount of water. Dosage of Nitroxoline is prescribed individually by physician.

Take the entire amount of Nitroxoline prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Nitroxoline?
Nitroxoline may cause the following side effects: Nausea, vomiting, decreased appetite, in rare cases skin rash, urticaria. In very rare cases Nitroxoline may cause tachycardia, ataxia, headache, liver dysfunction, paresthesia, polyneuropathy. In prolonged treatment neuritis of vision nerve is possible.

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Nitroxoline overdose symptoms?
If you overdose Nitroxoline, seek immediate medical attention. Overdose symptoms include: stomach disturbances, disorders of central nervous system, renal toxicity.

Which other medicines may affect Nitroxoline?
Nitroxoline may interact with the following groups of drugs:

  • Antacids
  • Nalidixic acid (quinolone)

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Nitroxoline, let your doctor know what other medicines, including OTC, you currently take.

How should I store Nitroxoline?
You should store the medication at dry and protected from light place out of reach of children. Do not store the medication in the bathroom.