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Generic Name (active ingredient): Ofloxacin
Brand Name: Ofloxacin, Floxin
Ofloxacin is an antimicrobial drug with broad spectrum of action from the group of fluoroquinolones.
How does the medication work?
Ofloxacin acts on the bacterial enzyme DNA gyrase that provides superhelix and thus stability of the DNA of bacteria (destabilization of the DNA chains leads to their death). Ofloxacin has bactericidal effect. It is active against organisms producing beta-lactamases and fast-growing atypical mycobacteria. Bacteria sensitive to Ofloxacin: Staphylococcus aureus, Staphylococcus epidermidis, Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter, Klebsiella spp. (including Klebsiella pneumonia), Enterobacter spp., Hafnia, Proteus spp. (including Proteus mirabilis, Proteus vulgaris), Salmonella spp., Shigella spp. (including Shigella sonnei), Yersinia enterocolitica, Campylobacter jejuni, Aeromonas hydrophila, Plesiomonas aeruginosa, Vibrio cholerae, Vibrio parahaemolyticus, Haemophilus influenzae, Chlamydia spp., Legionella spp., Serratia spp., Providencia spp., Haemophilus ducreyi, Bordetella parapertussis, Bordetella pertussis, Moraxella catarrhalis, Propionibacterium acne, Brucella spp. Different sensitivity to the drug have: Enterococcus faecalis, Streptococcus pyogenes, pneumoniae and viridans, Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter, Mycoplasma hominis, Mycoplasma pneumoniae, Mycobacterium tuberculosis, Mycobacterium fortuitum, Ureaplasma urealyticum, Clostridium perfringens, Corynebacterium spp., Helicobacter pylori, Listeria monocytogenes, Gardnerella vaginalis. In most cases, insensitive: Nocardia asteroides, anaerobic bacteria (eg Bacteroides spp., Peptococcus spp., Peptostreptococcus spp., Eubacter spp., Fusobacterium spp., Clostridium difficile). No effect on Treponema pallidum.
When Ofloxacin is prescribed?
What should I know before taking Ofloxacin?
Do not use this medication if you are allergic to Ofloxacin or to any other medicines such as:
Do not take Ofloxacin if any of the below conditions apply to you:
Before taking Ofloxacin, tell your health care provider about any other medicines you take or if you have any of the following disorders:
If you are pregnant, plan to become pregnant, or breastfeed, you should take Ofloxacin only under a strict control of your doctor. Ofloxacin belongs to a pregnancy category C meaning that it may harm the unborn baby and it passes into the breast milk. For this reason, breastfeeding must be stopped if Ofloxacin is prescribed.
How to take Ofloxacin:
Ofloxacin is available in the forms of tablets, oral solution, and injectable solution, eye drops, ear drops
Dosage of Ofloxacin is prescribed individually by physician.
Take the entire amount of Ofloxacin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.
What are the side effects of Ofloxacin?
Ofloxacin may cause the following side effects:
If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.
Which are Ofloxacin overdose symptoms?
If you overdose Ofloxacin, seek immediate medical attention. Overdose symptoms include: dizziness, confusion, lethargy, disorientation, drowsiness, vomiting
Which other medicines may affect Ofloxacin?
Ofloxacin may interact with the following groups of drugs:
For a complete list of possible interactions ask your doctor or pharmacist. Before taking Ofloxacin, let your doctor know what other medicines, including OTC, you currently take.
How should I store Ofloxacin?
The drug should be stored in a dry, protected from light place, out of the reach of children, at a temperature below 25 C (77 F).