Generic Name (active ingredient): Roxithromycin
Brand Name: Roxid, Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin

Roxithromycin is half synthetic macrolide antibiotic that is used to treat infections caused by susceptible microorganisms such as: respiratory tract infections, ENT infections, skin and soft tissue infections, gastroenterocolitis, stomach and duodenal ulcers, urogenital and other infections.

How does the medication work?
Roxithromycin belongs to a group of antibacterial medications called macrolides. Roxithromycin exerts bacteriostatic effects which is associated with inhibiting protein synthesis on ribosomes. The spectrum of activity include gram-positive and gram-negative microorganisms. Bacteroides fragilis, Mycobacterium hominis, Enterobacter spp. are resistant to Roxithromycin.

When Roxithromycin is prescribed?
Roxithromycin is used to treat infectious-inflammatory diseases caused by microorganisms sensitive to the drug:

  • Infection of the upper respiratory tract (including tonsillitis, pharyngitis, sinusitis, otitis media);
  • Infection of lower respiratory tract (pneumonia, including atypical pneumonia);
  • Infection of the urogenital tract (except for gonococcal infections);
  • Infections of skin and soft tissue (including acne vulgaris);
  • Odontogenic infection;
  • Acute gastroenteritis (caused by Campylobacter jejuni);
  • Duodenal ulcer and chronic gastritis (associated with Helicobacter pylori);
  • Infection caused by Mycoplasama spp., Chlamydia spp., Legionella spp.;
  • Chronic prostatitis;
  • Prevention of rheumatic fever;
  • Other infectious diseases in patients with known hypersensitivity to antibiotics, penicillin group.

What should I know before taking Roxithromycin?
Do not use this medication if you are allergic to Roxithromycin or to any other medicines such as:

  • Azithromycin, Erythromycin and other macrolide antibiotics

Do not take Roxithromycin if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients
  • Porphyria
  • Severe liver diseases
  • Severe kidney diseases
  • Pregnancy
  • Breastfeeding

Before taking Roxithromycin, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Liver diseases in anamnesis
  • Kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Roxithromycin only under a strict control of your doctor. Roxithromycin belongs to a pregnancy category B meaning that safety of the medication was not studied in pregnant women. Talk to your doctor about risks and benefits of taking Roxithromycin during pregnancy

How to take Roxithromycin:
Roxithromycin is available in the form of coated tablets. Tablets should be taken with sufficient amount of water swallowing whole. Dosage of Roxithromycin is prescribed individually by physician.

Take the entire amount of Roxithromycin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Roxithromycin?
Roxithromycin may cause the following side effects:

  • Digestive system: nausea, vomiting, stomach pain, diarrhea, increased activity of liver enzymes, in very rare cases - liver failure
  • Allergic reactions: erythema, skin rash, edema
  • Other: fever, headache, tinnitus, increased blood levels of eosinophils

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Roxithromycin overdose symptoms?
If you overdose Roxithromycin, seek immediate medical attention. Overdose symptoms include: nausea, vomiting, diarrhea.

Which other medicines may affect Roxithromycin?
Roxithromycin may interact with the following groups of drugs:

  • Ergot alkoloids
  • 5-HT4 receptor agonists (cisapride)
  • Antihistamines (terfenadine, astemizole)
  • Antipsychotics (pimozide)
  • Xantines (theophylline, midazolam)
  • Blood thinners (anticoagulants)
  • Insomnia treatment (midazolam)
  • Immunosuppressors (cyclosporine)
  • Other antibiotics
  • Cardiac glycosides (digoxin)

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Roxithromycin, let your doctor know what other medicines, including OTC, you currently take.

How should I store Roxithromycin?
Roxithromycin should be stored at dry and protected from light place out of reach of children. Do not store Roxithromycin tablets in the bathroom. © 2020