Other antibiotics / Spectinomycin

Spectinomycin

Generic Name (active ingredient): Spectinomycin
Brand Name: Trobicin

Spectinomycin is an aminocyclitol antibiotic produced by Streptomyces spectabilis. It is highly effective against Neisseria gonorrhoeae.

How does the medication work?
Spectinomycin belongs to a group of medicines called aminocyclitol antibiotics produced by Streptomyces spectabilis. Spectinomycin exerts bacteriostatic action that is associated with inhibiting the synthesis of proteins in the bacterial cells. Spectinomycin interacts with 30S ribosomal subunits leading disorders of ostomotic stability and lysis of microbial cells. Spectinomycin is highly effective against Neisseria gonorrhoeae.

When Spectinomycin is prescribed?

  • Acute gonorrheal urethritis and prostatitis in men
  • Acute gonorrheal cervicitis and proctitis in women

What should I know before taking Spectinomycin?
Do not use this medication if you are allergic to Spectinomycin or to any other medicines such as:

  • Streptomycin, Gentamycin, Kanamycin and other aminoglycoside antibiotics

Do not take Spectinomycin if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients

Before taking Spectinomycin, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Liver diseases in anamnesis
  • Kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Spectinomycin only under a strict control of your doctor. Spectinomycin belongs to a pregnancy category B meaning that safety of the medication was not studied in pregnant women. Talk to your doctor about risks and benefits of taking this medication during pregnancy.

How to take Spectinomycin:
Spectinomycin is available in the form of intramuscular infection. Injections should be made only by specialized medical staff. Dosage of Spectinomycin is prescribed individually by physician.

Take the entire amount of Spectinomycin prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Spectinomycin?
Spectinomycin may cause the following side effects:

Central nervous system: dizziness, insomnia.

Allergic reactions: skin rash (erythematous macular, sometimes generalized itching), urticaria, anaphylactic reactions.
Digestive system: nausea, cholestatic jaundice, increased alkaline phosphatase.
Urinary system: reduction of diuresis is not accompanied by impaired renal function, in some cases - hematuria, with prolonged use - increasing urea blood levels.
Laboratory tests: long-term use - reduction of hematocrit, hemoglobin levels and glutamine pyruvate transaminases in serum.
Local reactions: pain, redness, thrombophlebitis at place of injections
If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Spectinomycin overdose symptoms?
If you overdose Spectinomycin, seek immediate medical attention. Currently there no known any overdose effects associated with Spectinomycin injections.

Which other medicines may affect Spectinomycin?
Spectinomycin may interact with the following drugs:

  • Spectinomycin increases the toxicity of lithium preparations
  • Spectinomycin may interact with other antibiotics, especially with aminoglycosides

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Spectinomycin, let your doctor know what other medicines, including OTC, you currently take.

How should I store Spectinomycin?
Spectinomycin should be stored and dry and protected from light place out of reach of children at room temperature (not more than 30C). Do not store the medication in the bathroom.

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