Sulfodimidin

Generic Name (active ingredient): Sulfadimidine

Sulfadimidine is antibacterial preparation that belongs to a group of medicines called sulfonamides. It is used to treat bacterial infections caused by susceptible to Sulfadimidine microorganisms.

How does the medication work?
Sulfadimidine exerts antibacterial bacteriostatic action which is associated with inhibiting the acceptance by microorganisms of para-aminobenzoic acid or PABA and interfering with folate synthesis. Sulfadimidine is active against gram-negative and gram-positive microorganisms, Escherichia coli, Shigella spp., Klebsiella spp., Vibrio cholerae, Clostridium paraperfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydophila (Chlamydia) spp., Actinomyces israelii, Toxoplasma gondii.

When Sulfadimidine is prescribed?

  • Infectious-inflammatory diseases caused by sensitive microflora:
  • Tonsillitis
  • Bronchitis
  • Pneumonia
  • Infections of the bile passages
  • Infections of the urinary passages
  • Wound infection
  • Gonorrheal
  • Erysipelas
  • Dysentery
  • Toxoplasmosis
  • Nocardiasis

What should I know before taking Sulfadimidine?
Do not use this medication if you are allergic to Sulfadimidine or to any other medicines such as:

  • Sulfadimethoxine, sulfasalazine and other sulfa drugs

Do not take Sulfadimidine if any of the below conditions apply to you:

  • Hypersensitivity to any of the medication ingredients
  • Severe liver diseases
  • Severe kidney diseases
  • Hemopoietic system disorders
  • Deficiency of G6PD
  • Hyperbilirubinemia
  • Porphyria
  • Azotemia

Before taking Sulfadimidine, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • History of blood diseases
  • Liver and kidney diseases in anamnesis

If you are pregnant, plan to become pregnant, or breastfeed, you should take Sulfadimidine only under a strict control of your doctor. Sulfadimidine belongs to a pregnancy category C meaning that is not safe to use the medication during pregnancy because of high risk of teratogenic effect and embryotoxic effect.

How to take Sulfadimidine:
Sulfadimidine is available in the forms of tablets. Tablets should be taken with sufficient amount of water swallowing whole. Do not chew or crash the tablets. Dosage of Sulfadimidine is prescribed individually by physician.

Take the entire amount of Sulfadimidine prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Sulfadimidine?
Sulfadimidine may cause the following side effects: nausea, vomiting, diarrhea, crystalluria, leukopenia, agranulocytosis, agranulocytosis, allergic reactions.

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Sulfadimidine overdose symptoms?
If you overdose Sulfadimidine, seek immediate medical attention. Overdose symptoms include: diarrhea, vomiting, stomach pain.

Which other medicines may affect Sulfadimidine?
Sulfadimidine may interact with the following groups of drugs:

  • Bactericidal antibiotics
  • Antacids
  • NSAID's
  • Anticonvulsants (phenytoin)
  • Vitamins (ascorbic acid)
  • Thiamazole (antithyroid preparations)

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Sulfadimidine, let your doctor know what other medicines, including OTC, you currently take.

How should I store Sulfadimidine?
You should store the medication at dry and protected from light place out of reach of children. Do not store Sulfadimidine in the bathroom.

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