Choose Font Size: A
| |

Teicoplanin

Generic Name (active ingredient): Teicoplanin
Brand Name: Targocid

Teicoplanin is an antibiotic drug which belongs to a class of glycopeptides. The active ingredient was derived firstly from the culture of Actinoplanes teichomyceticus. The drug is effective against a large variety of bacterial microorganisms and is used in treatment of bacterial infection.

How does the medication work?
Teicoplanin is an antibacterial, bactericidal drug. The drug forms a complex in the bacterial cellular wall, blocks the formation of the wall, affects the cytoplasmatic membrane, inhibits the formation of spheroplasts. The preparation is absorbed well after intramuscular administration, bioavailability of the drug reaches 90%, protein binding reaches 90-95%. The preparation is slowly absorbed into the tissues, half-life of the drug is 150 hours. The drug is mainly excreted with urine(80%).

The preparation is active against methicillin and beta-lactam resistant staphylococci, streptococci, enterococci and other microorganisms. Resistance to the preparation is rarely developed, cross resistance to other antibiotic groups has not been registered.

When Targocid is prescribed?
The preparation is normally used in treatment of susceptible to the drug infections:

  • Skin and soft tissue infections
  • Respiratory infections
  • Urogenital infections
  • Bone and joint infections
  • Septicemia
  • Endocarditis
  • Peritonitis
  • IBS or irritable bowel syndrome
  • Infectious collitis

What should I know before taking Teicoplanin?
Do not use this medication if you are allergic to Targocid or to any other medicines such as:

  • Other glycopeptide antibiotics

Do not take Teicoplanin if any of the below conditions apply to you:

  • Hypersensitivity to any components of the preparation
  • During breastfeeding period
  • Liver failure
  • Renal failure

Before taking Targocid, tell your health care provider about any other medicines you take or if you have any of the following disorders:

  • Haemopoietic system pathologies
  • Hearing disorders

If you are pregnant, plan to become pregnant, or breastfeed, you should take Teicoplanin only under a strict control of your doctor. Targocid belongs to a pregnancy category C meaning that it should be used only in cases when no other treatment is effective, if potential benefits may warrant use of the drug in pregnant women despite potential risks.

How to take Teicoplanin:
Targocid is available in the forms of powder for injection.
Dosage of Teicoplanin is prescribed individually by physician.
Take the entire amount of Targocid prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.

What are the side effects of Teicoplanin?
Targocid may cause the following side effects:

  • Nausea
  • Vomiting
  • Diarrhea
  • Increased levels of liver transaminase
  • Flushing
  • Dizziness
  • Vestibular disorders
  • Headache
  • Dermatitis
  • Decreased hearing
  • Toxic skin necrosis
  • Steven-Johnson syndrome
  • Leukopenia
  • Neutropenia
  • Agranulocytosis
  • thrombocytopenia
  • Eosinophilia
  • Allergic reactions
  • Local reactions

If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.

Which are Teicoplanin overdose symptoms?
If you overdose Targocid, seek immediate medical attention.

Which other medicines may affect Teicoplanin?
Targocid may interact with the following groups of drugs:

  • Amynoglycosides
  • Antimycotics
  • Immunosuppressants
  • Diuretics

For a complete list of possible interactions ask your doctor or pharmacist. Before taking Targocid, let your doctor know what other medicines, including OTC, you currently take.

How should I store Teicoplanin?
The preparation should be kept at room temperatures, covered from direct sunlight. The drug should be kept away from children.