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Generic Name (active ingredient): Valganciclovir
Brand Name: Valcyte, Valixa, Cymeval
Valganciclovir is an antiviral prodrug used to treat cytomegalovirus infections.
How does the medication work?
Valganciclovir is a L-valyl ester of ganciclovir that is, after oral administration, quickly transformed into ganciclovir under the influence of intestinal and hepatic esterases. Ganciclovir inhibits the replication of the viruses of herpes group in vitro and in vivo. Human viruses sensitive to ganciclovir are cytomegalovirus (CMV), herpes simplex virus type 1 and type 2, human herpes virus (HHV-6, HHV-7, HHV-8), Epstein-Barr virus, Varicella zoster and hepatitis B.
When Valganciclovir is prescribed?
What should I know before taking Valganciclovir ?
Do not use this medication if you are allergic to Valgancyclovir or to any other medicines such as:
Do not take Valganciclovir if any of the below conditions apply to you:
Before taking Valganciclovir, tell your health care provider about any other medicines you take or if you have any of the following disorders:
If you are pregnant, plan to become pregnant, or breastfeed, you should take Valganciclovir only under a strict control of your doctor. Valganciclovir belongs to a pregnancy category C meaning that during pregnancy administration of the drug should be avoided unless the potential positive effects for the mother justifies the potential risk to the fetus. Nursing mothers should discontinue breastfeeding while on the therapy.
How to take Valganciclovir:
Valganciclovir is available in the form of coated tablets
Dosage of Valganciclovir is prescribed individually by physician.
Take the entire amount of Valganciclovir prescribed by your doctor, even if you feel better before the end of the treatment. If you stop taking medication too early, symptoms may return.
If you missed the scheduled dose, take the medication as soon as you remember, but skip the dose if it is almost the time for the following dose. Do not take two doses at once.
What are the side effects of Valganciclovir?
Valganciclovir may cause the following side effects:
Adverse effects identified in more than 5% of patients with CMV retinitis and after transplantation:
If you experience any side effect that last long or becomes bothersome, please inform your doctor as dose adjustment or treatment discontinuation may be required.
Which are Valgancyclovir overdose symptoms?
If you overdose Valgancyclovir, seek immediate medical attention. Overdose symptoms include: bone marrow suppression, nephrotoxicity, hematological toxicity, hepatotoxicity, gastrointestinal toxicity (abdominal pain, diarrhea, vomiting), neurotoxicity (generalized tremors, convulsions)
Which other medicines may affect Valganciclovir ?
Valganciclovir may interact with the following groups of drugs:
For a complete list of possible interactions ask your doctor or pharmacist. Before taking Valganciclovir, let your doctor know what other medicines, including OTC, you currently take.
How should I store Valganciclovir?
The drug should be stored out of reach of children at temperature below 30 ° C (86F).